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Male Factor Infertility

Causes of low sperm count: The various causes of low sperm count are as follows:

1) Hypogonadotropic Hypogonadism
:

a)       Deficiency of central sperm producing hormones as LH, FSH & other hormones may occur due to any of the below mentioned cause as Hypothalamic – pituitary deficiency: Idiopathic GnRH deficiency, Kallman syndrome, Prader-Willi syndrome, Laurence-Moon-Biedl syndrome, Hypothalamic deficiency, pituitary hypoplasia, Trauma, post surgical, postiradiation, Tumour (Adenoma, craniopharyngioma, other), Vascular (pituitary infraction, carotid aneurysm), Infiltrative (Sarcoidosis, histiocytosis, hemochromatosis) Autoimmune hypophysitis, Hypopituitarism, Pituitary, Hypothalamic, Associated with multiple pituitary hormone deficiencies: Idiopathic pan hypo pituitarism (hypothalamic defects), Pituitary dysgenesis, Space-occupying lesions (craniopharyngioma, Rathke pouch cysts, hypothalamic tumors, pituitary adenomas), , Laurence-Moon-Beidl syndrome Prader-Willi syndrome , Frohlich syndrome,

b)       Drugs (drug-induced hyperprolactinemia, sex steroids use), Glucocorticoid excess

c)        Isolated gonadotropin deficiency (non acquired)

 

 

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